Endocrine Abstracts

Introduction: Higher cortisol levels and, in particular, hyperactivity of the HPA axis might play a role in the development of MS at least in adults. Data on the pediatric age are scanty.Aim of our study was to evaluate ACTH and cortisol association with MS, its components, phenotypic parameters, family history of metabolic derangements in pediatric obesity.Methods: Cross-sectional study. 271 Caucasian overweight or obese children ...

Introduction: Aim of this study was to assess the prevalence of subclinical hypothyroidism in a paediatric population of overweight and obese children and its association with metabolic parameters and with metabolic syndrome (MS).Subjects and methods: Clinical and metabolic evaluations in 600 overweight and obese children and adolescents (310 females, 290 males, 260 prepubertal, 240 pubertal, mean age: 10.7±3.1 years) were performed. MS was defined ...

Introduction: Vitamin D plays an important role on musculoskeletal composition, but new evidences highlight others possible pleiotropic effects on many tissues and also metabolic functions. Vitamin D insufficiency should be associated with all-cause mortality, in particular with cardiovascular disease and metabolic syndrome. International studies suggested that 25(OH)D level sufficiency should be established at 30 ng/ml, insufficiency between 30 and 20 ng/ml and deficiency low...